FGF basic protein (30R-AF044)

Purified recombinant Human FGF basic protein

Synonyms Fibroblast Growth Factor-basic protein, HBGF-2 protein, FGF-2 protein, Prostatropin protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF basic protein corresponding to amino acids MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS.
Expression System E.coli
Purity > 95% pure
Molecular Weight 16.2 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is approximately 0.1 ng/ml corresponding to a specific activity of approximately 1 x 10^7 units/mg. Assay #2: The ED50 was dete

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance FGF basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF basic signals through FGFR 1b, 1c, 2c, 3c and 4.

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Availability: In stock

Price: $225.00
Size: 50 ug
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