FGF basic protein (30R-AF045)

Purified recombinant Human FGF basic protein

Synonyms Prostatropin protein, HBGF-2 protein, Fibroblast Growth Factor-basic protein, FGF-2 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF basic protein corresponding to amino acids PALPEDGGGA FPPGHFKDPK RLYCKNGGFF LRIHPDGRVD GVREKSDPHV KLQLQAEERG VVSIKGVCAN RYLAMKEDGR LLASKCVTEE CFFFERLESN NYNTYRSRKY SSWYVALKRT GQYKLGSKTG PGQKAILFLP MSAKS.
Expression System E.coli
Purity > 95% pure
Molecular Weight 16.3 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent stimulation of thymidine uptake by 3T3 cells is approximately 0.2 ng/ml corresponding to a specific activity of 5 x 10^6 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance FGF basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF basic signals through FGFR 1b, 1c, 2c, 3c and 4.

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Availability: In stock

Price: $225.00
Size: 50 ug
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