FGF12 protein (His tag) (80R-1091)
Purified recombinant Human FGF12 protein
|Synonyms||Fibroblast growth factor 12 FGF 12 protein, FGF-12 protein, Fibroblast growth factor homologous factor 1 protein, FGF12B protein, FGF 12, FGF12, FGF 12B protein, FGF-12, Fibroblast growth factor 12 protein, FGF12 protein, FHF1 protein, Fibroblast growth factor 12B protein, Myocyte activating factor., Fibroblast growth factor FGF 12b protein, FHF1 protein, FGF 12 protein, FHF 1 protein|
Coomassie Blue stained SDS-PAGE of FGF12 protein (His tag) (80R-1091)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-181 amino acids: MGSSHHHHHH SSGLVPRGSH MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKP IEVCMYREQS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS T|
|Purity||> 90% pure|
|Molecular Weight||22.6 kDa (201aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris, pH 7.5, containing 10% glycerol, 1mM DTT, and 2mM EDTA.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange. Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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