FGF19 protein (30R-AF035)

Purified recombinant Human FGF19 protein

Synonyms FGF 19 protein, FGF19, FGFJ protein, FGF-19, FGF 19, Fibroblast Growth Factor-19 protein, FGF-19 protein, FGF-19 protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of FGF19 protein corresponding to amino acids MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK.
Expression System E.coli
Purity > 95% pure
Molecular Weight 21.8 kDa
Form & Buffer Lyophilized from 5mM Tris, pH 7.6, with 75mM NaCl. Reconstitute in water to a concentration of 0.1-1.0 mg/ml.

Usage & Assay Information

Bioactivity Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance The FGF family plays central roles during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF19, a member of the FGF family, is a high affinity heparin dependent ligand for FGFR4. FGF19 is expressed during the brain development and embryogenesis.

References
Add a Paper

Ugo Borello, Inma Cobos, Jason E Long, Cornelis Murre, John LR Rubenstein

FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development

Neural Development

Issue: 2008, 3:17 DOI: 10.1186/1749-8104-3-17

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Availability: In stock

Price: $225.00
Size: 25 ug
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