FKBP1B protein (His tag) (80R-2019)

Recombinant human FKBP1B protein (His tag)

Synonyms Peptidyl-prolyl cis-trans isomerase FKBP1B protein, FKBPB-1, PKBP1L protein, FKBP12.6 protein, OTK4 protein, FKBP1L protein, FKBPB 1 protein, FKBP1B, FKBPB 1, PPIase protein, FKBPB-1 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of FKBP1B protein (His tag) (80R-2019)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-108 amino acids: MGSSHHHHHH SSGLVPRGSH RSMGVEIETI SPGDGRTFPK KGQTCVVHYT GMLQNGKKFD SSRDRNKPFK FRIGKQEVIK GFEEGAAQMS LGQRAKLTCT PDVAYGATGH PGVIPPNATL IFDVELLNLE
Expression System E.coli
Purity > 90% pure
Molecular Weight 14.2 kDa (130aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
Concentration 0.25 mg/ml

Usage & Assay Information

Usage Recommendations FKBP1B protein (His tag) has been used in SDS-PAGE, and may be suitable for use in other applications, to be determined by the end user.

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance FKBP1B, also known as peptidyl-prolyl cis-trans isomerase FKBP1B, is a member of the immunophilin protein family which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. Recombinant human FKBP1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of FKBP1B protein (His tag) (80R-2019) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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