FLIP antibody (10R-1124)

Mouse monoclonal FLIP antibody

Synonyms Monoclonal FLIP antibody, Anti-FLIP antibody, Cellular FLICE-like inhibitory protein antibody, I-FLICE antibody, Casper antibody, MRIT antibody, Caspase-like apoptosis regulatory protein antibody, CFLAR antibody, CASP8AP1 antibody, Caspase-eight-related protein antibody, Caspase homolog antibody, Inhibitor of FLICE antibody, CLARP antibody, CASP8 and FADD-like apoptosis regulator isoform 1 antibody, CASH antibody, MACH-related inducer of toxicity antibody, FLAME-1 antibody
Specificity Human
Cross Reactivity Human, Mouse, Rat
Applications ELISA, WB
Immunogen FLIP antibody was raised in mouse using recombinant human FLIP (1-376aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone 5D8
Isotype IgG3 kappa
Source Anti-human FLIP antibody, clone 5D8, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FLIP protein.
Method of Purification FLIP antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance FLIP, also known as CASP8 and FADD-like apoptosis regulator (CFLAR), contains two death effector domains (DEDs) and a caspase-like domain. FLIP may play a crucial role between cell survival and cell death pathway in mammalian cells and interacts with adapter protein FADD and caspase-8 and -10, and potently inhibits apoptosis induced by all known death receptors DR3 (death receptor 3), TRAIL-R (TNF-related apoptosis-inducing ligand receptor) and TNFR1 (tumor necrosis factor receptor 1).

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Availability: In stock

Price: $265.00
Size: 100 ul
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