FOXO1A antibody (10R-1609)

Mouse monoclonal FOXO1A antibody

Synonyms Monoclonal FOXO1A antibody, Anti-FOXO1A antibody, FKH1 antibody, FOXOA 1, FOXO1 antibody, FOXOA 1 antibody, FOXOA-1 antibody, Forkhead box protein O1 antibody, FOXOA-1, FOXO1A, FKHR antibody
Specificity Human FOXO1A
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen FOXO1A antibody was raised in mouse using recombinant Human Forkhead Box O1A (Rhabdomyosarcoma) (Foxo1A)

Images

Western Blot analysis of immunized recombinant protein using FOXO1A antibody (10R-1609)

Left: FOXO1A staining. Right: Coomassie Blue staining of immunized recombinant protein.

Specifications

Host Mouse
Clone 738C3a
Isotype IgG1
Method of Purification FOXO1A antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer FOXO1A antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance FOXO1 belongs to the forkhead family of transcription factors that are characterized by a distinct fork head domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. In hepatic cells this transcription factor seems to increase the expression of PEPCK and glycogen-6 phosphatase (the same enzymes that are blocked via the metformin/AMPK/SHP pathway). Blocking this transcription factor offers an opportunity for novel therapies for diabetes mellitus.

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Images

  • Western Blot analysis of immunized recombinant protein using FOXO1A antibody (10R-1609) | Left: FOXO1A staining. Right: Coomassie Blue staining of immunized recombinant protein.

Availability: In stock

Price: $190.00
Size: 50 ug
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