FOXP3 antibody (70R-14522)

Affinity purified rabbit polyclonal FOXP3 antibody

Synonyms Polyclonal FOXP3 antibody, Anti-FOXP3 antibody, Forkhead Box P3 antibody FOXP3, FOXP 3, FOXP-3, FOXP 3 antibody, FOXP-3 antibody
Cross Reactivity Bovine, Chicken, Horse, Human, Pig, Rat, Rhesus Monkey
Applications IHC-P, WB
Immunogen FOXP3 antibody was raised in Rabbit using a synthetic peptide corresponding to the exon 2 deletion site as the immunogen

Images

Western Blot analysis using FOXP3 antibody (70R-14522)

Western Blot analysis of FOXP3 in (A) FOXP3 transfected and (B) mock transfected cell lysate using FOXP3 antibody at 5 ug/ml

Specifications

Host Rabbit
Isotype IgG
Method of Purification FOXP3 antibody was purified by Protein G affinity chromatography
Form & Buffer Supplied in PBS buffer containing 0.2% gelatin and 0.05% sodium azide

Usage & Assay Information

Usage Recommendations WB: 2-5 ug/ml

Storage & Safety

Storage Store at 4 deg C for short term storage, for longer terms, store at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance One of the many immunotolerance mechanisms that the immune system has developed to distinguish between self and non-self antigens is regulatory T cells or Tregs. Several elegant experiments, using transgenic mice and retrovirus-mediated over expression studies, have led to the identification of FOXP3, a transcription factor, as a specific molecular marker essential for the development and function of Tregs. The primary evidence regarding the involvement of FOXP3 in the development of Tregs was provided in patients suffering from IPEX, a rare and fatal human autoimmune disease. The emergence of Tregs and the role of FOXP3 as a critical player in the negative control of various normal and pathological immune responses holds great promise for the development of novel therapies for autoimmune diseases.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using FOXP3 antibody (70R-14522) | Western Blot analysis of FOXP3 in (A) FOXP3 transfected and (B) mock transfected cell lysate using FOXP3 antibody at 5 ug/ml

Availability: In stock

Price: $295.00
Size: 100 ug
OR
Shipping
View Our Distributors