FSBP protein (His tag) (80R-2841)

Purified recombinant FSBP protein (His tag)

Synonyms FSBP, Fibrinogen silencer-binding protein, Fibrinogen silencer binding protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of FSBP protein (His tag) (80R-2841)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-299 aa: MGSSHHHHHH SSGLVPRGSH MGSMVGKARS SNFTLSEKLD LLKLVKPYVK ILEEHTNKHS VIVEKNRCWD IIAVNYNAIG VDRPPRTAQG LRTLYKRLKE YAKQELLQQK ETQSDFKSNI SEPTKKVMEM IPQISSFCLV RDRNHIQSAN LDEEAQAGTS SLQVMLDHHP VAITVEVKQE EDIKPPPPLV LNSQQSDTLE QREEHELVHV MERSLSPSLS SVDMRMTSSP SSIPRRDDFF RHESGEHFRS LLGYDPQILQ MLKEEHQIIL ENQKNFGLYV QEKRDGLKRR QQLEEELLRA KIEVEKLKAI RLRHDLPEYN SL
Expression System E.coli
Purity > 85% pure
Molecular Weight 37.2 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 1M Urea, 10% glycerol

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance Fibrinogen silencer-binding protein, also known as FSBP, is interacts with X11alpha. X11alpha/FSBP complex signals to the nucleus to repress glycogen synthase kinase-3beta promoter activity. X11alpha is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) through a centrally located phosphotyrosine binding domain to inhibit the production of Abeta peptide that is deposited in Alzheimer's disease brains. Recombinant human FSBP protein, fused to His-tag at N-terminus, was expressed in E.coli.

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Images

  • SDS-PAGE analysis of FSBP protein (His tag) (80R-2841) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $275.00
Size: 50 ug
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