GABARAPL2 protein (His tag) (80R-1643)
Purified recombinant Human GABARAPL2 protein
|Synonyms||ATG8 protein, GABARAPL 2 protein, Gamma-aminobutyric acid receptor-associated protein-like 2 protein, GABARAPL2, GABARAPL-2 protein, GATE-16 protein, ATG8C protein, GABARAPL-2, GATE16 protein, GABARAPL 2, GEF2|
Coomassie Blue stained SDS-PAGE of GABARAPL2 protein (His tag) (80R-1643)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-117 amino acids: MGSSHHHHHH SSGLVPRGSH MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF|
|Purity||> 90% pure|
|Molecular Weight||15.8 kDa (137aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.2M NaCl, 5mM DTT and 20% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||GABARAPL2, also known as ATG8, is involved in intra Golgi traffic and modulates intra Golgi transport through coupling between NSF activity and SNAREs activation. GABARAPL2 first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Recombinant human GABARAPL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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