GABRA3 antibody (70R-14979)

Rabbit polyclonal GABRA3 antibody

Synonyms Polyclonal GABRA3 antibody, Anti-GABRA3 antibody, GABRA 3 antibody, GABRA-3 antibody, GABRA3, Gamma-Aminobutyric Acid antibody, Gaba A Receptor Alpha 3 antibody
Applications IHC, WB

Images

Immunohistochemical staining using GABRA3 antibody (70R-14979)

Immunohistochemical staining of rat amygdala showing labeling of GABRA3 subunit

Specifications

Host Rabbit
Method of Purification GABRA3 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:100

General Information

Biological Significance GABAA receptors are members of the cys-loop family of ligand-gated ion channels, responsible for mediating the inhibitory effects of GABA alongside GABAB and GABAC receptors. They are pentameric proteins, consisting of 5 subunits belonging to different families (alpha1-6, beta1-3, gamma1-3, delta, pi, epsilon, rho, theta). The most abundant GABAA receptor in the mammalian brain consist of two copies each of alpha1 and beta2 with a single gamma2 subunits. GABAA receptors contain an integral chloride channel, and have modulatory sites for benzodiazepines, barbiturates, neurosteroids and ethanol.

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Images

  • Immunohistochemical staining using GABRA3 antibody (70R-14979) | Immunohistochemical staining of rat amygdala showing labeling of GABRA3 subunit
  • Western Blot analysis using GABRA3 antibody (70R-14979) | Western blot of mousebrain lysates from wild type (Control) and a-knockout (aK/O) animals showing specific immunolabeling of 53k subunit of GABRA3

Availability: In stock

Price: $335.00
Size: 100 ul
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