Galectin 4 protein (His tag) (80R-1208)
Purified recombinant Human Galectin 4 protein
|Synonyms||GAL 4 protein, protein NY CO 27 protein, Galectin-4 protein, Galectin 4 protein, Lactose binding lectin 4 protein, Lactose-binding lectin 4 protein, Lectin galactoside binding soluble 4 protein, Galectin-4, L36LBP protein, Galectin4 protein, Galectin 4, Galectin4, Galectin 4 protein, , Homo sapiens galectin4 mRNA complete cds protein, L 36 lactose binding protein protein, protein NYCO27 protein, L36 lactose binding protein protein, GAL4 protein, LGALS4 protein|
Coomassie Blue stained SDS-PAGE of Galectin 4 protein (His tag) (80R-1208)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-323 amino acids: MGSSHHHHHH SSGLVPRGSH MAYVPAPGYQ PTYNPTLPYY QPIPGGLNVG MSVYIQGVAS EHMKRFFVNF VVGQDPGSDV AFHFNPRFDG WDKVVFNTLQ GGKWGSEERK RSMPFKKGAA FELVFIVLAE HYKVVVNGNP FYEYGHRLPL QMVTHLQVDG DLQLQSINFI GGQPLRPQGP PMMPPYPGPG HCHQQLNSLP TMEGPPTFNP PVPYFGRLQG GLTARRTIII KGYVPPTGKS FAINFKVGSS GDIALHINPR MGNGTVVRNS LLNGSWGSEE KKITHNPFGP GQFFDLSIRC GLDRFKVYAN GQHLFDFAHR LSAFQRVDTL EIQGDVTLSY VQI|
|Purity||> 95% pure|
|Molecular Weight||38.1 kDa (343aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, and 1mM DTT.|
Usage & Assay Information
|Bioactivity||The ED50 for this effect is is 10 ? 20 ug/ml. Measured by its ability its ability to agglutinate human red blood cells|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Galectin-4 belongs to a subfamily of galectins composed of two carbohydrate recognition domains within the same peptide chain. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic reactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. Recombinant Galectin-4 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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