GAP43 antibody (20R-2854)

Chicken polyclonal GAP43 antibody

Synonyms Polyclonal GAP43 antibody, Anti-GAP43 antibody, GAP 43 antibody, GAP-43 antibody, GAP43, Growth Associated Protein 43 antibody
Applications IHC, WB

Images

Immunofluorescent staining using GAP43 antibody (20R-2854)

Immunofluorescent staining of mixed neuron/glial cultures showing GAP43 (green) labeling of numerous axonal and dendritic profiles and anti-alpha II spectrin (red)

Specifications

Host Chicken
Form & Buffer Supplied in liquid form in PBS + 10 mM NaN3

Usage & Assay Information

Usage Recommendations WB: 1:2000, IF: 1:500

General Information

Biological Significance GAP43, a common marker of differentiating neurons, is expressed at elevated levels by developing or regenerating neurons during axon growth. While GAP-43 is an integral membrane protein associated with the cytoplasmic surface of axonal growth cones (and synapses), it is absent from dendritic growth cones. In adult brain, GAP-43 is found in high concentration in presynaptic areas where memory formation is thought to occur, such as frontal cortex, limbic system and hippocampus.

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Images

  • Immunofluorescent staining using GAP43 antibody (20R-2854) | Immunofluorescent staining of mixed neuron/glial cultures showing GAP43 (green) labeling of numerous axonal and dendritic profiles and anti-alpha II spectrin (red)
  • Western Blot analysis using GAP43 antibody (20R-2854) | Western blot of rat cortex lysate showing specific immunolabeling of ~ 43k GAP43 protein

Availability: In stock

Price: $295.00
Size: 100 ul
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