GAPDH SO3 antibody (10R-8415)

Mouse monoclonal GAPDH SO3 antibody

Synonyms Monoclonal GAPDH SO3 antibody, Anti-GAPDH SO3 antibody, GAPDH antibody, glyceraldehyde-3-phosphate dehydrogenase antibody, 38 kDa BFA-dependent ADP-ribosylation substrate antibody, aging-associated gene 9 protein antibody, BARS-38 antibody, bb02e05 antibody, BOS_5957 antibody, CDABP0047 antibody, g3pd antibody, G3PDH antibody, gapd antibody, glyceraldehyde 3-phosphate dehydrogenase antibody, glyceraldehyde phosphate dehydrogenase antibody, glyceraldhyde 3-phosphate dehydrogenase antibody, glycerladehyde 3 phosphate dehydrogenase antibody, KNC-NDS6 antibody, Peptidyl-cysteine S-nitrosylase GAPDH antibody
Cross Reactivity Human
Applications WB
Immunogen GAPDH SO3 antibody was raised in Mouse using a sulfonylated peptide (KLH coupled) corresponding to the oxidation sensitive site sequence to human GAPDH as the immunogen

Images

Western Blot analysis using GAPDH SO3 antibody (10R-8415)

Specifications

Host Mouse
Clone 4A1
Isotype IgG1 kappa
Method of Purification GAPDH SO3 antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:200-1000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a catalytic enzyme commonly known to be involved in glycolysis. The enzyme exists as a tetramer of identical 37- kDa subunits. GAPDH catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, this ubiquitously expressed enzyme also displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Other studies also provide evidence of GAPDH playing an essential part of the program of gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. On recent study, GAPDH has identified of the most oxidant sensitive cell proteins.

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Images

  • Western Blot analysis using GAPDH SO3 antibody (10R-8415) |

Availability: In stock

Price: $295.00
Size: 100 ul
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