GATA2 antibody (10R-1758)

Mouse monoclonal GATA2 antibody

Synonyms Monoclonal GATA2 antibody, Anti-GATA2 antibody, GATA-2 antibody, GATA-2, MGC2306 antibody, GATA 2 antibody, GATA2, GATA binding protein 2 antibody, NFE1B antibody, GATA 2
Specificity Human GATA2
Cross Reactivity Human. Other species not studied
Applications Dot Blot, ICC
Immunogen GATA2 antibody was raised in mouse using recombinant Human Gata Binding Protein 2

Images

Western blot analysis using GATA2 antibody (10R-1758)

Specifications

Host Mouse
Clone 353C5a
Isotype IgG2b
Method of Purification GATA2 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer GATA2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The GATA family of transcription factors, which contain zinc fingers in their DNA binding domain, have emerged as candidate regulators of gene expression in hematopoietic cells. GATA1 is essential for normal primitive and definitive erythropoiesis and is expressed at high levels in erythroid cells, mast cells, and megakaryocytes. GATA2 is expressed in hematopoietic progenitors, including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. In chicken erythroid progenitors, forced expression of GATA2 promotes proliferation at the expense of differentiation. GATA3 expression is restricted to T-lymphoid cells and some nonhematopoietic cell types, including embryonic stem cells.

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Images

  • Western blot analysis using GATA2 antibody (10R-1758) |

Availability: In stock

Price: $190.00
Size: 50 ug
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