GDI2 antibody (70R-10549)
Affinity purified rabbit polyclonal GDI2 antibody
|Synonyms||Polyclonal GDI2 antibody, Anti-GDI2 antibody, GDI-2 antibody, GDP dissociation inhibitor 2 antibody, GDI2, GDI 2 antibody, GDI 2, GDI-2|
|Cross Reactivity||Human, Dog, Mouse, Rat, Bovine, Chicken, Pig, African Clawed Frog|
|Immunogen||GDI2 antibody was raised in rabbit using the C terminal of GDI2 as the immunogen|
|Assay Information||GDI2 Blocking Peptide, catalog no. 33R-2630, is also available for use as a blocking control in assays to test for specificity of this GDI2 antibody|
Western Blot analysis using GDI2 antibody (70R-10549)
Western Blot showing GDI2 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements.|
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