GIP protein (His tag) (80R-2766)

Purified recombinant GIP protein (His tag)

Synonyms Gastric inhibitory polypeptide protein, Glucose-dependent insulinotropic polypeptide protein, Gastric Inhibitory Peptide protein, GIP
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of GIP protein (His tag) (80R-2766)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 22-153 aa: MGSSHHHHHH SSGLVPRGSH MGSEKKEGHF SALPSLPVGS HAKVSSPQPR GPRYAEGTFI SDYSIAMDKI HQQDFVNWLL AQKGKKNDWK HNITQREARA LELAGQANRK EEEAVEPQSS PAKNPSDEDL LRDLLIQELL ACLLDQTNLC RLRSR
Expression System E.coli
Purity > 90% pure
Molecular Weight 17.3 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol 0.1M NaCl, 2mM DTT
Concentration 250 ug/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance GIP, also known as glucose-dependent insulinotropic polypeptide, is an important insulin-releasing hormone of the enteroinsular axis that has a functional profile of possible therapeutic value for type 2 diabetes. This protein is an important incretin hormone released into the circulation from endocrine K-cells of the duodenum and jejunum after ingestion of food1. It was evaluated for their ability to elevate cellular cAMP production and stimulate insulin secretion. It also promotes plasma triglyceride clearance in response to oral fat loading. In liver, GIP has been shown to enhance insulin-dependent inhibition of glycogenolysis. Recombinant human GIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

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Images

  • SDS-PAGE analysis of GIP protein (His tag) (80R-2766) | Figure annotation denotes ug of protein loaded and % gel used.
  • SDS-PAGE analysis of GIP protein (His tag) (80R-2766) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $365.00
Size: 50 ug
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