Glutamine Synthetase antibody (20R-2939)

Rabbit polyclonal Glutamine Synthetase antibody

Synonyms Polyclonal Glutamine Synthetase antibody, Anti-Glutamine Synthetase antibody, GLUL antibody, glutamate-ammonia ligase antibody, BOS_16078 antibody, cell proliferation-inducing protein 59 antibody, GLNS antibody, glutamate--ammonia ligase antibody, glutamate-ammonia ligase (glutamine synthase) antibody, glutamate-ammonia ligase (glutamine synthetase) antibody, glutamate decarboxylase antibody, glutamine synthase antibody, glutamine synthetase antibody, glutamine synthetase 1 antibody, Glutamine synthetase (glutamate-ammonia ligase) antibody, glutamine synthetase-like antibody, GS antibody, p42 antibody, PIG43 antibody, PIG59 antibody, proliferation-inducing protein 43 antibody
Cross Reactivity Human, Mouse, Rat
Applications WB
Immunogen Glutamine Synthetase antibody was raised in Rabbit using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using Glutamine Synthetase antibody (20R-2939)

Specifications

Host Rabbit
Isotype IgG
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:2000,

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Glutamine Synthetase is found in astrocytes as an octamer of identical 45 kDa subunits. Most well known function of GS is the detoxification of brain ammonia. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer?s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. On the other hand, the level of expression of GS is increased during ischemia in vivo or hypoxia in culture.

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Images

  • Western Blot analysis using Glutamine Synthetase antibody (20R-2939) |

Availability: In stock

Price: $295.00
Size: 100 ul
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