Glutathione Peroxidase I antibody (10R-8489)

Mouse monoclonal Glutathione Peroxidase I antibody

Synonyms Monoclonal Glutathione Peroxidase I antibody, Anti-Glutathione Peroxidase I antibody, GPX1 antibody, glutathione peroxidase 1 antibody, AL033363 antibody, BOS_20918 antibody, cellular glutathione peroxidase antibody, CGPx antibody, cytosolic glutathione peroxidase antibody, glutathione peroxidase type 2 antibody, Gpx antibody, GPx-1 antibody, GPXD antibody, GSHPx antibody, gshpx1 antibody, GSHPx-1 antibody, putative glutathione peroxidase antibody, TNeu078a18.1 antibody
Cross Reactivity Human, Mouse, Rat
Applications ELISA, IP, WB
Immunogen Glutathione Peroxidase I antibody was raised in Mouse using a recombinant mouse protein purified from E.coli (Gpx1) as the immunogen

Images

Western Blot analysis using Glutathione Peroxidase I antibody (10R-8489)

Specifications

Host Mouse
Clone 13B2AF
Isotype IgG1 kappa
Method of Purification Glutathione Peroxidase I antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1: 5000, IP: 1 ul

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPxfamily to be discovered. GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract. Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation. Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxylipids in low density lipoprotein orthymine. All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.

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Images

  • Western Blot analysis using Glutathione Peroxidase I antibody (10R-8489) |

Availability: In stock

Price: $295.00
Size: 100 ul
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