GM-CSF protein (30R-AG022)

Purified recombinant Human GM-CSF protein

Synonyms Granulocyte/Macrophage Colony-Stimulating Factor protein, MGI-1GM protein, GM-CSF protein, CSF-2 protein, pluripoietin-alpha protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of GM-CSF protein corresponding to amino acids MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK.
Expression System E.coli
Purity > 98% pure
Molecular Weight 14.5 kDa
Form & Buffer Lyophilized from 10mM tris, pH 8.5.

Usage & Assay Information

Bioactivity The ED50 was determined by the dose-dependent stimulation of the proliferation of Mouse FDC-P1 cells is 1.0 x 10^8 units/mg.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and Mouse molecules are species-specific and exhibit no cross-species reactivity.

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Availability: In stock

Price: $225.00
Size: 20 ug
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