Goat anti Human IgE (70R-IG015)

Affinity purified Goat anti Human IgE antibody

Synonyms Polyclonal Goat anti Human IgE antibody, Anti-Goat anti Human IgE antibody, Human IgE antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA, ICC, IHC, WB

Specifications

Host Goat
Isotype IgG
Method of Purification Goat anti Human IgE antibody was purified by affinity chromatography.
Form & Buffer Supplied as a liquid in PBS, pH 7.2 with 0.1% NaN3.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: coating:1:100-1:500, primary:1:1,000-1:30,000, ICC: 1:200-1:2,000, IHC: 1:200-1:2,000, WB: colorimetric: 1:1,000-1:10,000, chemiluminescent: 1:1,000-1:30,000

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance IgE is the least abundant immunoglobulin in plasma, found at a concentration of less that 0.6 micrograms/ml of normal plasma. Elevated IgE levels are found in patients experiencing severe allergic reactions and parasitic infections. In a myeloma condition, IgE is produced by a single clone of plasma cells. The structure of myeloma IgE, however, is normal, and the immunoglobulin purified from a myeloma source is a useful protein for studying immunoglobulin behavior.

References
Add a Paper

Rosa M. Ten, Melissa J. McKinstry, Gary D. Bren, Carlos V. Paya

Signal transduction pathways triggered by the FcϵRIIb receptor (CD23) in human monocytes lead to nuclear factor-κB activation

Journal of Allergy and Clinical Immunology

Volume: 104 Issue: 2 Page: 376-387 DOI: 10.1016/S0091-6749(99)70382-9

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Availability: In stock

Price: $295.00
Size: 1 mg
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