Goat anti Human Kappa light chain (20-S2301G000-S4)

Goat anti Human Kappa light chain antibody

Synonyms Polyclonal Goat anti Human free Kappa Light Chain antibody,Goat anti-Human free Kappa Light Chain antibody, Human free Kappa Light Chain antibody
Specificity Human
Cross Reactivity Monospecific for Kappa Light Chain.
Applications User optimized
Immunogen Kappa light chain antibody was raised in goat using kappa light chain isolated from human bance-Jones urine as the immunogen.

Specifications

Host Goat
Purity Standard grade
Form & Buffer Supplied delipidated, defibrinated, and 0.2 um filtered in 0.2M Tris, pH 7.6, with 0.5M NaCl and 0.09% NaN3.
Concentration 1.56 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance There are two types of light chain in humans (as in other mammals), kappa chain, encoded by the immunoglobulin kappa locus ([email protected]) on chromosome 2 and lambda chain, encoded by the immunoglobulin lambda locus ([email protected]) on chromosome 22. Antibodies are produced by B lymphocytes, each expressing only one class of light chain. Once set, light chain class remains fixed for the life of the B lymphocyte. In a healthy individual, the total kappa to lambda ratio is roughly 2:1 in serum (measuring intact whole antibodies) or 1:1.5 if measuring free light chains, with a highly divergent ratio indicative of neoplasm.

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Availability: In stock

Price: $100.00
Size: 10 ml
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