Goat anti Mouse IgG1 (Alexa Fluor 488) (43R-1649)

Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Synonyms Goat anti Mouse Immunoglobulin G1 secondary antibody, Mouse Immunoglobulin G1 antibody
Specificity Mouse IgG1 Fc gamma specific
Cross Reactivity Minimal cross reactivity with human, bovine and rabbit serum proteins. Does not react with other mouse IgG subtypes, IgM or the Fab portion of mouse IgG1.
Applications ELISA, Immunoassays

Specifications

Host Goat
Isotype IgG1
Method of Purification Goat anti Mouse IgG1 was purified by affinity chromatography
Tag/Conjugate Alexa Fluor 488
Form & Buffer Suppliedas a lyophilized powderin 0.01M sodium phosphate, 0.25 M NaCl, pH 7.6, and 0.05% sodium azide, with 15 mg/ml BSA.
Concentration 1.4 mg/ml

Usage & Assay Information

Usage Recommendations Dilution Range of 1:100 - 1:800 for most applications

Storage & Safety

Storage Store at 2-8 deg C

General Information

Biological Significance Antibodies are major components of the immune system. IgG is the main antibody isotype found in blood and extracellular fluid allowing it to control infection of body tissues. By binding many kinds of pathogens—representing viruses, bacteria, and fungi—IgG protects the body from infection. It does this via several immune mechanisms: IgG-mediated binding of pathogens causes their immobilization and binding together via agglutination; IgG coating of pathogen surfaces (known as opsonization) allows their recognition and ingestion by phagocytic immune cells; IgG activates the classical pathway of the complement system, a cascade of immune protein production that results in pathogen elimination; IgG also binds and neutralizes toxins.

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Availability: In stock

Price: $395.00
Size: 500 ug
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