GREM2 protein (His tag) (80R-2754)

Purified recombinant GREM2 protein (His tag)

Synonyms Gremlin-2 precursor protein, CKTSF1B2 protein, DAND3 protein, PRDC protein, GREM2, GREM-2, GREM 2
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of GREM2 protein (His tag) (80R-2754)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 22-168 aa: MGSSHHHHHH SSGLVPRGSH MGSRKNRPAG AIPSPYKDGS SNNSERWQHQ IKEVLASSQE ALVVTERKYL KSDWCKTQPL RQTVSEEGCR SRTILNRFCY GQCNSFYIPR HVKKEEESFQ SCAFCKPQRV TSVLVELECP GLDPPFRLKK IQKVKQCRCM SVNLSDSDKQ
Expression System E.coli
Purity > 85% pure
Molecular Weight 19 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Concentration 1 mg/ml

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance GREM2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this protein belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this protein may play a role in regulating organogenesis, body patterning, and tissue differentiation. Recombinant human GREM2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

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Images

  • SDS-PAGE analysis of GREM2 protein (His tag) (80R-2754) | Figure annotation denotes ug of protein loaded and % gel used.
  • SDS-PAGE analysis of GREM2 protein (His tag) (80R-2754) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $270.00
Size: 100 ug
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