GRIA1 antibody (Ser831) (70R-14999)

Rabbit polyclonal GRIA1 antibody (Ser831)

Synonyms Polyclonal GRIA1 antibody, Anti-GRIA1 antibody, GRIA 1 antibody, GRIA-1 antibody, GRIA1, glutamate receptor ionotropic antibody, AMPA1 antibody, alpha 1 antibody, 2900051M01Rik antibody, AI853806 antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody
Applications WB

Images

Western Blot analysis using GRIA1 antibody (Ser831) (70R-14999)

Western blot of rat hippocampal lysate showing specific immunolabeling of ~100k GluR1 protein phosphorylated at Ser831 (Control)

Specifications

Host Rabbit
Method of Purification GRIA1 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance GRIA1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

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Images

  • Western Blot analysis using GRIA1 antibody (Ser831) (70R-14999) | Western blot of rat hippocampal lysate showing specific immunolabeling of ~100k GluR1 protein phosphorylated at Ser831 (Control)

Availability: In stock

Price: $335.00
Size: 150 ul
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