GRIA1 antibody (Ser845) (70R-15000)

Rabbit polyclonal GRIA1 antibody (Ser845)

Synonyms Polyclonal GRIA1 antibody, Anti-GRIA1 antibody, GRIA 1 antibody, GRIA-1 antibody, GRIA1, glutamate receptor ionotropic antibody, AMPA1 antibody, alpha 1 antibody, 2900051M01Rik antibody, AI853806 antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody
Applications IHC, WB

Images

Western Blot analysis using GRIA1 antibody (Ser845) (70R-15000)

Western blot of rat hippocampal lysate showing specific immunolabeling of ~100k GluR1protein phosphorylated at Ser845 (Control)

Specifications

Host Rabbit
Method of Purification GRIA1 antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:1000

General Information

Biological Significance AMPA receptors are members of the ionotropic class of glutamate receptors, which also includes NMDA and kainate receptors. AMPA receptors mediate fast excitatory synaptic transmission in the CNS and play a key role in hippocampal synaptic long-term potentiation (LTP) and depression (LTD). AMPA receptors consist of GluR1-4 subunits which assemble as homomers or heteromers to form functional AMPA receptors. The subunit composition determines the physiological properties of AMPA receptors: those containing the GluR2 subunit show low permeability to Ca2+ whereas those lacking this subunit show high Ca2+ permeability.

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Images

  • Western Blot analysis using GRIA1 antibody (Ser845) (70R-15000) | Western blot of rat hippocampal lysate showing specific immunolabeling of ~100k GluR1protein phosphorylated at Ser845 (Control)

Availability: In stock

Price: $335.00
Size: 150 ul
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