GRIN1 antibody (Splice Variant C1) (70R-15018)

Rabbit polyclonal GRIN1 antibody (Splice Variant C1)

Synonyms Polyclonal GRIN1 antibody, Anti-GRIN1 antibody, GRIN 1 antibody, GRIN-1 antibody, GRIN1, Glutamate receptor subunit zeta 1 antibody, NMDAR1 antibody, NMDA NR1 Subunit antibody
Applications IHC, WB

Images

Western Blot analysis using GRIN1 antibody (Splice Variant C1) (70R-15018)

Western blot of 10 ug of HEK 293 cells expressing: Lane 1 - HEK cells without NR1 expression(Mock), Lane 2 - NR1 subunit containing only the C2 Insert, Lane 3 - NR1 subunit containing the C1 and C2' Insert, Lane 4 - NR1 subunit containing the N1 and C2' Insert showing specific immunolabeling of ~120k NR1 subunit of the NMDA receptor containing the C1 splice variant insert

Specifications

Host Rabbit
Method of Purification GRIN1 antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:1000-1:2000

General Information

Biological Significance GRIN1 is an NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.

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Images

  • Western Blot analysis using GRIN1 antibody (Splice Variant C1) (70R-15018) | Western blot of 10 ug of HEK 293 cells expressing: Lane 1 - HEK cells without NR1 expression(Mock), Lane 2 - NR1 subunit containing only the C2 Insert, Lane 3 - NR1 subunit containing the C1 and C2' Insert, Lane 4 - NR1 subunit containing the N1 and C2' Insert showing specific immunolabeling of ~120k NR1 subunit of the NMDA receptor containing the C1 splice variant insert

Availability: In stock

Price: $335.00
Size: 25 ug
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