GRIN1 antibody (Splice Variant C2) (70R-15020)
Rabbit polyclonal GRIN1 antibody (Splice Variant C2)
|Synonyms||Polyclonal GRIN1 antibody, Anti-GRIN1 antibody, GRIN 1 antibody, GRIN-1 antibody, GRIN1, Glutamate receptor subunit zeta 1 antibody, NMDAR1 antibody, NMDA NR1 Subunit antibody|
Western Blot analysis using GRIN1 antibody (Splice Variant C2) (70R-15020)
Western blot of 10 ug of HEK 293 cells expressing: Lane 1 - HEK cells without NR1 expression(Mock), Lane 2 - NR1 subunit containing only the C2 Insert, Lane 3 - NR1 subunit containing the C1 and C2' Insert, Lane 4 - NR1 subunit containing the N1 and C2' Insert showing specific immunolabeling of ~120k NR1 subunit of the NMDA receptor containing the C2’ splice variantinsert.
|Method of Purification||GRIN1 antibody was purified by affinity chromatography|
|Form & Buffer||Supplied in lyophilized form|
Usage & Assay Information
|Usage Recommendations||WB: 1:1000, IHC: 1:1000-1:2000|
|Biological Significance||GRIN1 is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits.|
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