GRIN2B antibody (70R-15025)

Rabbit polyclonal GRIN2B antibody

Synonyms Polyclonal GRIN2B antibody, Anti-GRIN2B antibody, GRIN 2B antibody, GRIN-2B antibody, GRIN2B, Glutamate Receptor Ionotropic N-Methyl D-Aspartate 2B antibody, MGC142178 antibody, MGC142180 antibody, NMDAR2B antibody, NR2B antibody, hNR3 antibody
Applications IHC, IP, WB

Images

Western Blot analysis using GRIN2B antibody (70R-15025)

Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDA receptor

Specifications

Host Rabbit
Method of Purification GRIN2B antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations WB: 1:1000, IHC: 1:1000, IP: 3 ug per 200 ug

General Information

Biological Significance N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

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Images

  • Western Blot analysis using GRIN2B antibody (70R-15025) | Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDA receptor

Availability: In stock

Price: $335.00
Size: 10 ug
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