GRIN2B antibody (Ser1480) (70R-15031)

Rabbit polyclonal GRIN2B antibody (Ser1480)

Synonyms Polyclonal GRIN2B antibody, Anti-GRIN2B antibody, GRIN 2B antibody, GRIN-2B antibody, GRIN2B, Glutamate Receptor Ionotropic N-Methyl D-Aspartate 2B antibody, MGC142178 antibody, MGC142180 antibody, NMDAR2B antibody, NR2B antibody, hNR3 antibody
Applications WB

Images

Western Blot analysis using GRIN2B antibody (Ser1480) (70R-15031)

Western blot of rat hippocampal lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDAR phosphorylated at Ser1480 (Control)

Specifications

Host Rabbit
Method of Purification GRIN2B antibody was purified by affinity chromatography
Form & Buffer Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:1000

General Information

Biological Significance The NMDA (N-methyl D-aspartate) receptors in the brain play a critical role in synaptic plasticity, synaptogenesis and excitotoxicity. NMDA R1 and combination of one or more NMDAR2 subunits forms NMDA receptor glutamate-gated ion channels. In this hetromer complex, NMDA R1 binds to co-agonist glycine and NMDA R2 binds to neurotransmitter glutamate (1). Several studies have suggested that protein phosphorylation of NMDA receptors may affect channel function, and additionally regulate these receptors’ synaptic trafficking and surface expression.

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Images

  • Western Blot analysis using GRIN2B antibody (Ser1480) (70R-15031) | Western blot of rat hippocampal lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDAR phosphorylated at Ser1480 (Control)

Availability: In stock

Price: $335.00
Size: 100 ul
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