GSTA4 protein (His tag) (80R-2245)
Purified recombinant Human GSTA4 Protein (His tag)
|Synonyms||GSTA-4 protein, GSTA4-4 protein, GSTA 4, GSTA-4, GSTA 4 protein, GTA4 protein, GSTA4, Glutathione S-transferase alpha 4 protein|
Coomassie Blue stained SDS-PAGE of GSTA4 protein (His tag) (80R-2245)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||MGSSHHHHHH SSGLVPRGSH MGSHMAARPK LHYPNGRGRM ESVRWVLAAA GVEFDEEFLE TKEQLYKLQD GNHLLFQQVP MVEIDGMKLV QTRSILHYIA DKHNLFGKNL KERTLIDMYV EGTLDLLELL IMHPFLKPDD QQKEVVNMAQ KAIIRYFPVF EKILRGHGQS FLVGNQLSLA DVILLQTILA LEEKIPNILS AFPFLQEYTV KLSNIPTIKR FLEPGSKKKP PPDEIYVRTV YNIFRP|
|Purity||> 95% pure|
|Molecular Weight||28.3 kDa|
|Form & Buffer||Supplied in liquid form in 20 mM Tris-HCl buffer, pH 8.0, 20% glycerol, 2mM DTT, 100mM NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products.|
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