GTF2B protein (His tag) (80R-1236)
Purified recombinant Human GTF2B protein
|Synonyms||TF2B protein, GTFB-2 protein, TFIIB protein, GTF2B, S300 II protein, General transcription factor IIB General transcription factor TFIIB protein, GTF2B protein, GTFB 2, Transcription initiation factor IIB., TF IIB protein, GTFB-2, GTFB 2 protein, RNA polymerase II transcription factor IIB protein|
Coomassie Blue stained SDS-PAGE of GTF2B protein (His tag) (80R-1236)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-316 amino acids: MGSSHHHHHH SSGLVPRGSH MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECGLV VGDRVIDVGS EWRTFSNDKA TKDPSRVGDS QNPLLSDGDL STMIGKGTGA ASFDEFGNSK YQNRRTMSSS DRAMMNAFKE ITTMADRINL PRNIVDRTNN LFKQVYEQKS LKGRANDAIA SACLYIACRQ EGVPRTFKEI CAVSRISKKE IGRCFKLILK ALETSVDLIT TGDFMSRFCS NLCLPKQVQM AATHIARKAV ELDLVPGRSP ISVAAAAIYM ASQASAEKRT QKEIGDIAGV ADVTIRQSYR LIYPRAPDLF PTDFKFDTPV DKLPQL|
|Purity||> 90% pure|
|Molecular Weight||36.9 kDa (336aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 0.1 M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||GTF2B, also known as transcription factor II B, is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. The protein serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. It is involved in the selection of the transcription start site. Recombinant GTF2B protein was expressed in E. coli and purified by using conventional chromatography techniques.|
Sorry, but there are no references currently for this product.
Sorry there are currently no reviews for this product