GTF2H2 antibody (10R-1271)

Mouse monoclonal GTF2H2 antibody

Synonyms Monoclonal GTF2H2 antibody, Anti-GTF2H2 antibody, TFIIH antibody, General transcription factor IIH subunit 2 antibody, GTFH-2, T-BTF2P44 antibody, GTFH-2 antibody, GTFH 2 antibody, BTF2 antibody, BTF2P44 antibody, GTF2H2, GTFH 2
Specificity Human GTF2H2
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen GTF2H2 antibody was raised in mouse using recombinant Human General Transcription Factor Iih, Polypeptide 2, 44Kda

Images

Western Blot analysis of immunized recombinant protein using GTF2H2 antibody (10R-1271)

Specifications

Host Mouse
Clone GTF2F6A10
Isotype IgG1
Method of Purification GTF2H2 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer GTF2H2 antibody in PBS (3.0 mM KCl,1.5 mM KH2PO4, 140 mM NaCl, 8.0 mM Na2HP04 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair.

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Images

  • Western Blot analysis of immunized recombinant protein using GTF2H2 antibody (10R-1271)

Availability: In stock

Price: $190.00
Size: 50 ug
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