H2AFY2 antibody (70R-2109)

Rabbit polyclonal H2AFY2 antibody raised against the middle region of H2AFY2

Synonyms Polyclonal H2AFY2 antibody, Anti-H2AFY2 antibody, HAF-2, HAF 2, HAF 2 antibody, HAF-2 antibody, H2AF, H2A Histone Y2 antibody, macroH2A2 antibody
Specificity H2AFY2 antibody was raised against the middle region of H2AFY2
Cross Reactivity Human
Applications WB
Immunogen H2AFY2 antibody was raised using the middle region of H2AFY2 corresponding to a region with amino acids KKGGKKSKAAKPRTSKKSKPKDSDKEGTSNSTSEDGPGDGFTILSSKSLV
Assay Information H2AFY2 Blocking Peptide, catalog no. 33R-4465, is also available for use as a blocking control in assays to test for specificity of this H2AFY2 antibody

Images

Western Blot analysis using H2AFY2 antibody (70R-2109)

H2AFY2 antibody (70R-2109) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 40 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of H2AFY2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.

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Images

  • Western Blot analysis using H2AFY2 antibody (70R-2109) | H2AFY2 antibody (70R-2109) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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