HADH protein (His tag) (80R-1272)
Purified recombinant Human HADH protein
|Synonyms||AB binding alcohol dehydrogenase protein, mitochondrial Hydroxyacyl Coenzyme A dehydrogenase type II protein, M/SCHAD protein, Mental retardation X linked syndromic 11 protein, Hydroxyacyl CoA Dehydrogenase type II protein, Endoplasmic reticulum associated amyloid beta peptide binding protein protein, Endoplasmic Reticulum Amyloid Binding Protein protein, Short chain dehydrogenase/reductase family 5C member 1 protein, MRPP2 protein, Amyloid beta peptide binding protein protein, SCHAD protein, HADH1 protein, Ads9 protein, Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 protein, Amyloid beta binding polypeptide protein, Type 10 17beta hydroxysteroid dehydrogenase protein, HADH 2 protein, Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase protein, HCD2 protein, Mitochondrial RNase P protein 2 protein, ABAD protein, ER associated a+myloid beta-binding protein protein, Mitochondrial ribonuclease P protein 2 protein, HHF4 protein, Amyloid beta peptide binding alcohol dehydrogenase protein, 17b HSD10 protein, Short chain type dehydrogenase/reductase XH98G2 protein, MRX17 protein, MHBD protein, XH98G2., 3 hydroxy 2 methylbutyryl CoA dehydrogenase protein, 3 hydroxyacyl CoA dehydrogenase type II protein, 17 beta hydroxysteroid dehydrogenase 10 protein, SDR5C1 protein, 17 beta hydroxysteroid dehydrogenase type 10 protein, ERAB protein, HAD protein, HADH2 protein, DUPXp11.22 protein, Hydroxyacyl-coenzyme A dehydrogenase protein, Hydroxysteroid (17 beta) dehydrogenase 10 protein, Type 10 17b HSD protein, CAMR protein, Type II HADH protein, HCD 2 protein, 3 hydroxyacyl CoA dehydrogenase type 2 protein, HSD17B10 protein|
Coomassie Blue stained SDS-PAGE of HADH protein (His tag) (80R-1272)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||13-314 amino acids: MGSSHHHHHH SSGLVPRGSH MSSSSTASAS AKKIIVKHVT VIGGGLMGAG IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENPKAGDE FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ KTFESLVDFS KALGKHPVSC KDTPGFIVNR LLVPYLMEAI RLYERGDASK EDIDTAMKLG AGYPMGPFEL LDYVGLDTTK FIVDGWHEMD AENPLHQPSP SLNKLVAENK FGKKTGEGFY KYK|
|Purity||> 95% pure|
|Molecular Weight||35.1 kDa (323aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||HADH, which belongs to the family of oxidoreductases, is important for converting certain fats to energy. This protein is an enzyme that catalyzes the chemical reaction; (S)-3-hydroxyacyl-CoA + NAD+ <=>3-oxoacyl-CoA + NADH + H+. It is also involved in a process called fatty acid oxidation, in which several enzymes work in a step-wise fashion to break down (metabolize) fats and convert them to energy. Recombinant HADH protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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