HAND1 antibody (10R-1997)
Mouse monoclonal HAND1 antibody
|Synonyms||Monoclonal HAND1 antibody, Anti-HAND1 antibody, HAND1, HAND-1, HAND-1 antibody, HAND 1, Heart and Neural Crest Derivatives Expressed 1 antibody, HAND 1 antibody|
|Immunogen||HAND1 antibody was raised in Mouse using a purified recombinant fragment of HAND1(aa90-190) expressed in E. coli as the immunogen.|
Western Blot analysis using HAND1 antibody (10R-1997)
Western Blot showing HAND1 antibody used against truncated Trx-HAND1 recombinant protein (1).
|Form & Buffer||Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.|
Usage & Assay Information
|Usage Recommendations||ELISA: 1:10,000, WB: 1:500-1:2000|
Storage & Safety
|Storage||Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||HAND1 belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.|
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