Haptoglobin protein (30C-CP3018)

Purified native Human Haptoglobin protein

Synonyms HP protein, Haptoglobin, HPT protein, beta polypeptide protein, HP2 alpha2 protein, Haptoglobin protein, MGC111141 protein, HPA1S protein, alpha polypeptide protein, Hp2 alpha protein
Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human plasma
Purity > 95% pure
Molecular Weight Hp 1-1: 86 kDa; Hp 2-1: 200 kDa; Hp 2-2: 400 kDa
Form & Buffer Supplied as a lyophilised powder. Reconstitute with 1.0 ml of PBS, pH 7.4, per 1.0 mg of antigen.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance An acute-phase plasma protein found in human plasma at 100-300 mg per 100 ml. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes. Hp 1-1 is the most common, and the most effective in binding free hemoglobin. Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

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Availability: In stock

Price: $214.80
Size: 1 mg
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