HAX1 protein (His tag) (80R-2673)
Purified recombinant HAX1 protein (His tag)
|Synonyms||HCLS1 associated protein X-1 isoform a protein, HCLSBP1 protein, HS1BP1 protein, SCN3 protein, HAX1, HAX 1, HAX-1, HAX 1 protein, HAX-1 protein|
SDS-PAGE analysis of HAX1 protein (His tag) (80R-2673)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-279 aa: MGSSHHHHHH SSGLVPRGSH MSLFDLFRGF FGFPGPRSHR DPFFGGMTRD EDDDEEEEEE GGSWGRGNPR FHSPQHPPEE FGFGFSFSPG GGIRFHDNFG FDDLVRDFNS IFSDMGAWTL PSHPPELPGP ESETPGERLR EGQTLRDSML KYPDSHQPRI FGGVLESDAR SESPQPAPDW GSQRPFHRFD DVWPMDPHPR TREDNDLDSQ VSQEGLGPVL QPQPKSYFKS ISVTKITKPD GIVEERRTVV DSEGRTETTV TRHEADSSPR GDPESPRPPA LDDAFSILDL FLGRWFRSR|
|Purity||> 80% pure|
|Molecular Weight||33.7 kDa|
|Form & Buffer||Supplied in liquid form in 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl|
Storage & Safety
|Storage||Can be stored at 4 deg C for short terms (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles|
|Biological Significance||HAX1 is known to associate with HS1, a substrate of Src family tyrosine kinases. It also interacts with the product of PKD2, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with F-actin-binding protein, cortactin. It is associated with autosomal recessive severe congenital neutropenia, also known as Kostmann syndrome. Recombinant human HAX1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.|
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