HDAC1 antibody (10R-1580)

Mouse monoclonal HDAC1 antibody

Synonyms Monoclonal HDAC1 antibody, Anti-HDAC1 antibody, HDA 1c antibody, HD1 antibody, HDA-1c antibody, DKFZp686H12203 antibody, HDAC1, HDA 1c, GON-10 antibody, HDA-1c, Histone deacetylase 1 antibody, RPD3 antibody, RPD3L1 antibody
Specificity Human HDAC1
Cross Reactivity Human, Mouse, Rat. Other species not studied
Applications Dot Blot, ICC, WB
Immunogen HDAC1 antibody was raised in mouse using recombinant Human Histone Deacetylase 1 (Hdac1)

Images

Immunofluorescent staining using HDAC1 antibody (10R-1580)

Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-HDAC1 antibody.

Specifications

Host Mouse
Clone 730C6a
Isotype IgG1
Method of Purification HDAC1 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer HDAC1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-2 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumorsuppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

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Images

  • Immunofluorescent staining using HDAC1 antibody (10R-1580) | Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.01% Triton-X100 in PBS. The cells were immunostained with anti-HDAC1 antibody.
  • Western Blot analysis of immunized recombinant protein using HDAC1 antibody (10R-1580)

Availability: In stock

Price: $190.00
Size: 50 ug
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