HDAC8 protein (His tag) (80R-2071)

Recombinant human HDAC8 protein (His tag)

Synonyms RPD3 protein, HDAC-8 protein, CDA07 protein, HDAC8, HDAC 8 protein, HDAC 8, HDACL1 protein, HDAC-8, Histone deacetylase 8 protein, HD8 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of HDAC8 protein (His tag) (80R-2071)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-377 amino acids: MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL HKQMRIVKPK VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH RIQQILNYIK GNLKHVVHHH HHH
Expression System Sf-9 insect cells
Purity > 80% pure
Molecular Weight 42.6 kDa (383aa)
Tag/Conjugate His tag
Form & Buffer Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Concentration 0.25 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Can be stored at 4 deg C short term (1-2 weeks). For long term storage, aliquot and store at -20 deg C or -70 deg C. Avoid repeated freezing and thawing cycles.

General Information

Biological Significance HDAC8, also known as histone deacetylase 8, belongs to class 1 of the histone deacetylase/acuc/apha family. This protein is biologically involved in skull morphogenesis and metabolic control of the ERR-alpha/PGC1-alpha transcriptional complex. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Recombinant human HDAC8 protein, fused to His-tag at C-terminus, was expressed in Sf9 insect cell and purified by using conventional chromatography.

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Images

  • Coomassie Blue stained SDS-PAGE of HDAC8 protein (His tag) (80R-2071) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $365.00
Size: 50 ug
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