He-dcyd antibody (20R-1421)

Goat polyclonal He-dcyd antibody

Synonyms Polyclonal He-dcyd antibody, Anti-He-dcyd antibody, Heptanone-etheno-2?-Deoxycytidine antibody, He dcyd antibody, Heptanone etheno 2 Deoxycytidine antibody, Hedcyd antibody
Specificity Heptanone-etheno-2?-Deoxycytidine
Applications ELISA
Immunogen He-dcyd antibody was raised in Goat using Heptanone-etheno-2'-Deoxycytidine as the immunogen.

Specifications

Host Goat
Form & Buffer Whole serum supplied in liquid form with 0.01% Thimerosal and 0.1% Sodium Azide.

Usage & Assay Information

Usage Recommendations ELISA: >1:10,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Heptanone-etheno-2'-Deoxycytidine isa free-radical modified DNA adduct that may serve as a marker for cancer. HedC has been shown to be highly mutagenic in both bacterial and human cells. When an HedC adduct was placed in a plasmid that was replicated in both bacterial and human cells, it was able to completely block DNA replication in the bacteria and only small fractions of progeny were detected in the human cells suggesting that HedC is a very strong block to DNA synthesis. Additionally, HedC also strongly miscodes when bypassed in bacterial and human cell systems resulting in a miscoding frequency of about 45% and 90% respectively.

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Availability: In stock

Price: $625.00
Size: 1 ml
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