HEPACAM2 protein (His tag) (80R-2993)

Purified recombinant HEPACAM2 protein (His tag)

Synonyms HEPACAM family member 2 isoform 1 protein, MIKI protein, HEPACAM 2 protein, HEPACAM-2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of HEPACAM2 protein (His tag) (80R-2993)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 32-351 aa: MGSSHHHHHH SSGLVPRGSH MGSLKVTVPS HTVHGVRGQA LYLPVHYGFH TPASDIQIIW LFERPHTMPK YLLGSVNKSV VPDLEYQHKF TMMPPNASLL INPLQFPDEG NYIVKVNIQG NGTLSASQKI QVTVDDPVTK PVVQIHPPSG AVEYVGNMTL TCHVEGGTRL AYQWLKNGRP VHTSSTYSFS PQNNTLHIAP VTKEDIGNYS CLVRNPVSEM ESDIIMPIIY YGPYGLQVNS DKGLKVGEVF TVDLGEAILF DCSADSHPPN TYSWIRRTDN TTYIIKHGPR LEVASEKVAQ KTMDYVCCAY NNITGRQDET HFTVIITSVG LEKLAQKGKS LSP
Expression System E.coli
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage, for long term storage aliquot and store at -20 deg C or -70 deg C, avoid repeated freeze thaw cycles.

General Information

Biological Significance Norrin precursor, also known as NDP, is a secreted regulatory protein. It activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. This protein plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. It may be involved in a pathway that regulates neural cell differentiation and proliferation.

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Images

  • SDS-PAGE analysis of HEPACAM2 protein (His tag) (80R-2993) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $275.00
Size: 50 ug
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