HePTP antibody (10R-8587)

Mouse monoclonal HePTP antibody

Synonyms Monoclonal HePTP antibody, Anti-HePTP antibody, PTPN7 antibody, protein tyrosine phosphatase antibody, non-receptor type 7 antibody, BOS_16142 antibody, BPTP-4 antibody, dual specificity phosphatase 1 antibody, hematopoietic protein-tyrosine phosphatase antibody, HEPTP antibody, Lcptp antibody, LC-PTP antibody, LPTP antibody, protein-tyrosine phosphatase LC-PTP antibody, protein-tyrosine phosphatase antibody, non-receptor type 7 antibody, protein-tyrosine phosphatase antibody, nonreceptor-type antibody, stress induced antibody, PTPNI antibody, RP11-294K24.3 antibody, tyrosine-protein phosphatase non-receptor type 7 antibody
Cross Reactivity Human
Applications ELISA, WB
Immunogen HePTP antibody was raised in Mouse using a recombinant human protein purified from E.coli as the immunogen

Images

Western Blot analysis using HePTP antibody (10R-8587)

Specifications

Host Mouse
Clone AFPK32
Isotype IgG1 kappa
Method of Purification HePTP antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

Usage & Assay Information

Usage Recommendations WB: 1:5000

Storage & Safety

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

General Information

Biological Significance Hematopoietic tyrosine phosphatase (HePTP, PTPN7) belongs to a subgroup of PTPases with two other members, STEP and PCPTP1. HePTP is a 38 kDa class I non-receptor protein tyrosine phosphatase (PTP) that is strongly expressed in T cells. The protein consists of a short, amino-terminal extension that contains a conserved 16-amino acid kinase interaction motif (KIM) and a carboxy-terminal protein tyrosine phosphatase domain. HePTP binds the MAPK family kinases, Erk1/2 and p38 via KIM. Erk phosphorylates HePTP (at Thr45 and Ser72) and HePTP dephosphorylates Erk (at Tyr185).

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Western Blot analysis using HePTP antibody (10R-8587) |

Availability: In stock

Price: $295.00
Size: 100 ul
OR
Shipping
View Our Distributors