HER2 antibody (10R-1924)

Mouse monoclonal HER2 antibody

Synonyms Monoclonal HER2 antibody, Anti-HER2 antibody, HER-2 antibody, HER 2, HER-2, HER 2 antibody, HER 2 antibody, HER2, HER-2 antibody
Cross Reactivity Human
Applications ELISA, IHC, WB
Immunogen HER2 antibody was raised in Mouse using a purified recombinant fragment of HER-2 expressed in E. coli as the immunogen.

Images

Immunohistochemical staining using HER2 antibody (10R-1924)

Immunohistochemical analysis of paraffin-embedded human breast intraductal carcinama tissue(A) and breast infiltrating ductal carcinama tissue(B) showing membrane localization using HER-2 antibody with DAB staining.

Specifications

Host Mouse
Clone 9B9D8
Isotype IgG2b
Form & Buffer Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Storage & Safety

Storage Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. It is encoded within the genome by HER2/neu, a known proto-oncogene. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. However, ErbB receptors dimerise on ligand binding, and HER2 is the preferential dimerisation partner of other members of the ErbB family.

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Images

  • Immunohistochemical staining using HER2 antibody (10R-1924) | Immunohistochemical analysis of paraffin-embedded human breast intraductal carcinama tissue(A) and breast infiltrating ductal carcinama tissue(B) showing membrane localization using HER-2 antibody with DAB staining.
  • Western Blot analysis using HER2 antibody (10R-1924) | Western Blot showing HER-2 antibody used against truncated HER-2 recombinant protein.

Availability: In stock

Price: $295.00
Size: 100 ul
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