HES2 protein (His tag) (80R-2966)

Purified recombinant IMPACT protein (His tag)

Synonyms Transcription factor HES-2 protein, bHLHb40 protein, hairy and enhancer of split 2 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

SDS-PAGE analysis of HES2 protein (His Tag) (80R-2966)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-173 aa: MGSSHHHHHH SSGLVPRGSH MGSMGLPRRA GDAAELRKSL KPLLEKRRRA RINQSLSQLK GLILPLLGRE NSNCSKLEKA DVLEMTVRFL QELPASSWPT AAPLPCDSYR EGYSACVARL ARVLPACRVL EPAVSARLLE HLWRRAASAT LDGGRAGDSS GPSAPAPAPA SAPEPASAPV PSPPSPPCGP GLWRPW
Expression System E.coli
Purity > 80% pure
Molecular Weight 20.9 kDa
Tag/Conjugate His tag
Form & Buffer Supplied in liquid form in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for up to 2 weeks. For long term storage, aliquot and store at -20 deg C to -70 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Hairy and enhancer of split 2, also known as HES2, is a member of the HES family and contains one basic helix-loop-helix (bHLH) domain and one orange domain. The HES family members form a complex with TLE, the mammalian homologue of Groucho, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins. Activation of Notch signaling pathway leads to activation of HES family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). HES2 is expressed in a variety of adult and embryonic tissue.

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Images

  • SDS-PAGE analysis of HES2 protein (His Tag) (80R-2966) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: $275.00
Size: 50 ug
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