HEXA antibody (70R-14324)

Affinity purified Rabbit polyclonal HEXA antibody

Synonyms Polyclonal HEXA antibody, Anti-HEXA antibody, TSD antibody, MGC99608 antibody, hexosaminidase A, alpha polypeptide antibody
Applications IHC-P, WB
Immunogen HEXA antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence in the middle regionof human HEXA, different from the related rat and Rabbit sequencesby one amino acid, as the immunogen

Images

Immunohistochemical staining using HEXA antibody (70R-14324)

Immunohistochemistry of paraffin-embedded section of Human Intestinal Cancer Tissue

Specifications

Host Rabbit
Isotype IgG
Method of Purification HEXA antibody was purified by affinity chromatography
Form & Buffer Supplied in lyophilized form

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C for short term storage. For long term storage aliquot and store at -20 deg C, avoid repeated freeze/thaw cycles.

General Information

Biological Significance This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).

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Images

  • <div><font face=Calibri size=2>Immunohistochemical staining using HEXA antibody (70R-14324)</font></div>     | Immunohistochemistry of paraffin-embedded section of Human Intestinal Cancer Tissue
  • <div><font face=Calibri size=2>Western Blot analysis using HEXA antibody (70R-14324)</font></div>     | Lane 1: Rat Liver Tissue Lysate; Lane 2: Hela Cell Lysate; Lane 3: SMMC Cell Lysate

Availability: In stock

Price: $270.00
Size: 100 ug
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