Hexokinase 2 antibody (70R-5559)

Rabbit polyclonal Hexokinase 2 antibody raised against the N terminal of HK2

Synonyms Polyclonal Hexokinase 2 antibody, Anti-Hexokinase 2 antibody, Hexokinase Type 2 antibody, Hexokinase Type 2, Hexokinase Type 2, HXK2 antibody, Hexokinase Type -2 antibody, HK2 antibody, HKII antibody, Hexokinase Type -2, DKFZp686M1669 antibody, Hexokinase Type 2 antibody
Specificity Hexokinase 2 antibody was raised against the N terminal of HK2
Cross Reactivity Human,Mouse,Rat
Applications WB
Immunogen Hexokinase 2 antibody was raised using the N terminal of HK2 corresponding to a region with amino acids GTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMRGSG
Assay Information Hexokinase 2 Blocking Peptide, catalog no. 33R-3606, is also available for use as a blocking control in assays to test for specificity of this Hexokinase 2 antibody

Images

Immunohistochemical staining using Hexokinase 2 antibody (70R-5559)

Hexokinase 2 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 102 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of HK2 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.

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Images

  • Immunohistochemical staining using Hexokinase 2 antibody (70R-5559) | Hexokinase 2 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml. Magnification is at 400X
  • Western Blot analysis using Hexokinase 2 antibody (70R-5559) | Hexokinase 2 antibody (70R-5559) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: $345.00
Size: 50 ug
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