HIRIP3 antibody (10R-1507)

Mouse monoclonal HIRIP3 antibody

Synonyms Monoclonal HIRIP3 antibody, HIRA interacting protein 3 antibody, HIRIP-3 antibody, Anti HIRIP3 antibody, HIRIP3, HIRIP-3, HIRIP 3 antibody, HIRIP 3
Specificity Human HIRIP3
Cross Reactivity Human. Other species not studied
Applications Dot Blot
Immunogen HIRIP3 antibody was raised in mouse using recombinant Human Hira Interacting Protein 3

Images

Western Blot analysis of immunized recombinant protein using HIRIP3 antibody (10R-1507)

Specifications

Host Mouse
Clone 2415C2a
Isotype IgG1
Method of Purification HIRIP3 antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Form & Buffer HIRIP3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3 ).
Concentration 100 ug/ml

Usage & Assay Information

Usage Recommendations To be optimized by the end user.

Storage & Safety

Storage Store at 2-8 deg C for up to one year. We recommend long term storage at -20 deg C. Avoid repeated freezing and thawing.
Biohazard Information This antibody solution contains sodium azide (NaN ) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water. It is strongly adv

General Information

Biological Significance The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Recently, several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the HIRIP3 gene product binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Images

  • Western Blot analysis of immunized recombinant protein using HIRIP3 antibody (10R-1507)

Availability: In stock

Price: $190.00
Size: 50 ug
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