HIV1 gp41 protein (30-AH83)

Purified recombinant HIV1 gp41 protein

Synonyms HIV-1 gp41 protein, SU antigen, Surface protein antigen, HIV1 gp41, Envelope surface glycoprotein gp41 antigen, HIV-1 gp41, Human Immunodeficiency Virus 1 antigen, gp41 antigen, HIV 1 gp41, HIV 1 gp41 protein, gp41 glycoprotein antigen, gp41 antigen, Glycoprotein 41 antigen, HIV 1 gp41 antigen, HIV-1 gp41 antigen
Species Viral
Protein Type Recombinant
Applications ELISA, WB


Expression System Yeast
Purity > 99% pure
Form & Buffer Liquid in 1.0M urea , 0.5M sodium chloride, and 0.02M sodium phosphate, pH 7.4
Concentration Batch dependent - please inquire should you have specific requirements

Storage & Safety

Storage Aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles

General Information

Biological Significance HIV gp41 is a glycoprotein subunit that remains non-covalently-bound to gp120, and provides the second step by which HIV enters the cell. It is originally buried within the viral envelope, but, when gp120 binds to a CD4, gp120 changes its conformation, causing gp41 to become exposed, where it can assist in fusion with the host cell. The Env gene does not, in fact, code for gp120 and gp41, but for a precursor to both, gp160. During HIV reproduction, the host cell's own enzymes cleave gp160 into gp120 and gp41.

Add a Paper

David Opalka, Antonello Pessi, Elisabetta Bianchi, Gennaro Ciliberto, William Schleif, Michael McElhaugh, Renee Danzeisen, Romas Geleziunas, Michael Miller, Debra M. Eckert, David Bramhill, Joseph Joyce, James Cook, William Magilton, John Shiver, Emilio Emini, Mark T. Esser

Analysis of the HIV-1 gp41 specific immune response using a multiplexed antibody detection assay

Journal of Immunological Methods

Volume: 287 Issue: 1-2 Page: 49-65 DOI: 10.1016/j.jim.2004.01.016

Sean X. Du, Rebecca J. Idiart, Ellaine B. Mariano, Helen Chen, Peifeng Jiang, Li Xu, Kristin M. Ostrow, Terri Wrin, Pham Phung, James M. Binley, Christos J. Petropoulos, John A. Ballantyne, Robert G. Whalen

Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein


Volume: 395 Issue: 1 Page: 33-44 DOI: 10.1016/j.virol.2009.07.042


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Availability: In stock

Price: $95.00
Size: 100 ug
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