HIV1 tat HxB2 protein (FITC) (65-017003)

Purified recombinant HIV1 tat HxB2 (FITC)

Synonyms HIV 1 Tat interacting protein 60kDa protein, ESA1 protein, 60 kDa Tat interactive protein, Human tat interactive protein mRNA complete cds protein, cPLA protein, Tat interactive protein (60kD) protein, PLIP protein, Transactivating regulatory protein protein , TIP60 protein, HIV-1 tat protein, HTATIP1 protein, TIP protein, HIV-1 tat, HIV1 tat, HIV 1 tat protein, HIV 1 Tat interacting protein protein, HIV 1 tat, HIV 1 tat protein, HIV-1 tat protein, EC protein, Histone acetyltransferase HTATIP protein, Tat protein
Species Viral
Protein Type Recombinant
Applications ELISA, WB
Assay Information This protein contains a histidine-rich 12 amino acid leader sequence and is t-cell trophic. Recognized by Monoclonal and Polyclonal antibodies to tat (HIV-1) in ELISA and Western Blot.


Expression System E.coli
Purity > 90% pure
Tag/Conjugate FITC
Form & Buffer Supplied lyophilized with no preservatives added.
Concentration 50 ug/vial

Usage & Assay Information

Usage Recommendations ELISA: 1:1500-1:1000, FC: 1:200, WB: 1:500-1:1000

Storage & Safety

Storage Store lyophilized product at 2-8 deg C short term, following reconstitution, aliquot and store at -70 deg C or lower. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Tat vastly increases the level of transcription of the HIV dsRNA. Before Tat is present, a small number of RNA transcripts will be made, which allow the Tat protein to be produced. Tat then binds to cellular factors and mediates their phosphorylation, resulting in increased transcription of all HIV genes, providing a positive feedback cycle. This in turn allows HIV to have an explosive response once a threshold amount of Tat is produced, a useful tool for defeating the body's response.

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Availability: In stock

Price: $395.00
Size: 50 ug
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